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How does SageMD Omega support better health?
SageMD Omega delivers EPA and DHA omega-3 fatty acids in phospholipid form from sustainable Antarctic krill. Unlike fish oil where omega-3s are bound to triglycerides, krill oil contains omega-3s bound to phospholipids—the same type of molecules that make up your cell membranes. This molecular similarity may facilitate more efficient absorption and incorporation into cells. Plus, our krill oil includes naturally occurring astaxanthin, a powerful antioxidant that gives krill their reddish color and provides additional cellular protection.*
How does the 60 day trial work?
We're confident in SageMD Omega's benefits. Try it for 60 days and if you're not experiencing better overall wellness, simply email us for a complete refund. No complicated return process, no questions asked—just email and we'll refund your purchase promptly.
How does the subscription work?
Our subscription plans are designed for convenience and savings. Choose from 1 month (single bottle), 3 months (3 bottles delivered every 3 months with savings), or 6 months (6 bottles delivered every 6 months with greater savings). All subscription plans include free shipping and the ability to pause or cancel anytime through your account.
Is it worth subscribing?
Omega-3 fatty acids need consistent daily intake to maintain optimal levels in your cells and tissues. Research shows it takes weeks to build up EPA and DHA in red blood cells (the omega-3 index), and these levels drop when you stop supplementing. Our subscription ensures you maintain consistent omega-3 status for ongoing cardiovascular, brain, and joint support.*
SageMD Omega - Krill Oil
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*We recommend 3-6 months of consistent use for best results
Supports heart, brain, and joint health with phospholipid-bound omega-3s and astaxanthin*
Support cardiovascular and brain health with EPA and DHA*
Phospholipid form for efficient omega-3 absorption*
Includes astaxanthin for antioxidant support*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
How does SageMD Omega support better health?
SageMD Omega delivers EPA and DHA omega-3 fatty acids in phospholipid form from sustainable Antarctic krill. Unlike fish oil where omega-3s are bound to triglycerides, krill oil contains omega-3s bound to phospholipids—the same type of molecules that make up your cell membranes. This molecular similarity may facilitate more efficient absorption and incorporation into cells. Plus, our krill oil includes naturally occurring astaxanthin, a powerful antioxidant that gives krill their reddish color and provides additional cellular protection.
How does the 60 day trial work?
We're confident in SageMD Omega's benefits. Try it for 30 days and if you're not experiencing better overall wellness, simply email us for a complete refund. No complicated return process, no questions asked—just email and we'll refund your purchase promptly.
How does the subscription work?
Our subscription plans are designed for convenience and savings. Choose from 1 month (single bottle), 3 months (3 bottles delivered every 3 months with savings), or 6 months (6 bottles delivered every 6 months with greater savings). All subscription plans include free shipping and the ability to pause or cancel anytime through your account.
Is it worth subscribing?
Omega-3 fatty acids need consistent daily intake to maintain optimal levels in your cells and tissues. Research shows it takes weeks to build up EPA and DHA in red blood cells (the omega-3 index), and these levels drop when you stop supplementing. Our subscription ensures you maintain consistent omega-3 status for ongoing cardiovascular, brain, and joint support.
Phospholipid-Bound
Omega-3s
Sustainable Antarctic
Krill (NKO)
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Is Your Fish Oil Actually Getting Absorbed?
Most omega-3 supplements use triglyceride-bound fish oil, but your cell membranes are made of phospholipids—not triglycerides.
If you're taking omega-3 supplements for heart and brain health, you might assume your body is absorbing them efficiently. But there's an important detail most people miss: the molecular form matters.
Here's what's happening: Standard fish oil contains omega-3s bound to triglycerides. Your body has to break down these triglycerides, absorb the omega-3s, and then rebuild them into phospholipids before they can integrate into your cell membranes where they provide their health benefits.
That's a lot of metabolic work.
Krill oil takes a different approach. The omega-3s are already bound to phospholipids—the same type of molecules that make up your cell membranes. This molecular compatibility may allow for more efficient absorption and incorporation into the cells where omega-3s do their work.
Research suggests that phospholipid-bound omega-3s may be absorbed more efficiently than triglyceride forms, potentially allowing lower doses to achieve similar blood levels of EPA and DHA.
But many krill oil products on the market contain low levels of phospholipids—sometimes as little as 20%. Without adequate phospholipid content, you're not getting the full bioavailability advantage.
SageMD Omega solves this with 40% phospholipid content and sustainable NKO krill oil.
The Good News: Better Omega-3 Absorption Is Within Reach
You can support your heart, brain, and joints with omega-3s that are designed for efficient absorption.
SageMD Omega delivers EPA and DHA in their natural phospholipid form, matching the molecular structure of your cell membranes for optimal integration.
No fishy aftertaste...
No large, hard-to-swallow capsules...
Just clean, efficient omega-3 nutrition from sustainable Antarctic krill.
Your Path to Optimal Omega-3 Status
Discover how SageMD Omega delivers omega-3s in the form your body can use most efficiently, supporting cardiovascular health, brain function, and joint comfort.
Phospholipid-Bound for Better Absorption
PROBLEM: Traditional fish oil contains omega-3s bound to triglycerides. Your body must break down these triglycerides, absorb the free fatty acids, then rebuild them into phospholipids before they can integrate into cell membranes. This multi-step process may limit how efficiently your body uses the omega-3s you consume.
SOLUTION: SageMD Omega delivers EPA and DHA already bound to phospholipids—the same molecules that make up your cell membranes. Research suggests that phospholipid-bound omega-3s may integrate into cells more efficiently than triglyceride forms. This means your body can use the omega-3s you take more effectively, potentially requiring lower doses to achieve optimal tissue levels.
Support Cardiovascular Health
PROBLEM: Your cardiovascular system relies on omega-3 fatty acids for maintaining healthy cell membrane fluidity, supporting normal inflammatory processes, and maintaining healthy triglyceride levels already within normal range. Many people don't get adequate EPA and DHA from diet alone, especially as modern diets contain less fish and seafood than traditional diets.
SOLUTION: SageMD Omega provides 195mg of EPA and DHA per serving to support cardiovascular health. EPA and DHA help maintain healthy endothelial function (the cells lining your blood vessels), support normal cardiac rhythm, and help maintain healthy triglyceride levels already in normal range. Consistent omega-3 supplementation supports overall cardiovascular wellness.
Support Brain Health and Cognitive Function
PROBLEM: Your brain is nearly 60% fat by dry weight, and DHA is one of the most abundant fatty acids in brain cell membranes. DHA supports membrane fluidity, neurotransmitter function, and healthy brain cell communication. As you age, maintaining optimal DHA levels becomes increasingly important for cognitive health, but dietary intake often falls short.
SOLUTION: SageMD Omega delivers DHA in phospholipid form, which research suggests may cross the blood-brain barrier more efficiently than triglyceride-bound DHA. This supports optimal DHA incorporation into brain cell membranes where it helps maintain cognitive function, supports memory, and promotes overall brain health throughout life.
Support Joint Comfort and Flexibility
PROBLEM: Joint health depends on maintaining a healthy inflammatory response. Omega-3 fatty acids help support the body's natural resolution of inflammation, but the typical Western diet contains far more omega-6 fatty acids (which can be pro-inflammatory when out of balance) than omega-3s. This imbalance can affect joint comfort and flexibility over time.
SOLUTION: SageMD Omega provides EPA and DHA to help balance your omega-6 to omega-3 ratio, supporting a healthy inflammatory response. EPA is particularly important for joint health—it's a precursor to resolvins and protectins, specialized molecules your body makes to support the natural resolution of inflammation and promote joint comfort.
Antioxidant Protection with Astaxanthin
PROBLEM: Omega-3 fatty acids are polyunsaturated, meaning they contain multiple double bonds that make them susceptible to oxidation. When omega-3s oxidize, they can form harmful compounds that reduce the supplement's effectiveness and may even contribute to oxidative stress in your body. Fish oil is particularly vulnerable to oxidation during processing and storage.
SOLUTION: SageMD Omega naturally contains astaxanthin, one of nature's most powerful antioxidants. Astaxanthin protects the omega-3s from oxidation and provides additional antioxidant benefits throughout your body. It concentrates in cell membranes alongside omega-3s, protecting cells from oxidative damage and supporting healthy aging. You get omega-3 protection and whole-body antioxidant support in one supplement.
Sustainable and Pure
PROBLEM: Many fish oil supplements come from fish higher up the food chain that may accumulate environmental contaminants like mercury, PCBs, and dioxins. Even with purification, there are concerns about sustainability of fishing practices and environmental impact. You want omega-3s that are both pure and environmentally responsible.
SOLUTION: SageMD Omega uses NKO krill oil from sustainable Antarctic krill (Euphausia superba). Krill are tiny crustaceans low on the food chain, so they accumulate fewer contaminants than larger fish. The Antarctic fishery is strictly regulated for sustainability, with careful catch limits to protect the ecosystem. You get pure, clean omega-3s with minimal environmental impact.
SageMD Omega: Omega-3s in Nature's Preferred Form
Pure, sustainable, and formulated for optimal absorption. Our NKO krill oil provides EPA and DHA in phospholipid form for efficient cellular integration.
Experience better omega-3 absorption and utilization with just 2 small softgels daily.
Better health through intelligent omega-3 delivery with SageMD Omega.
Phospholipid-Bound Omega-3s
The omega-3s in SageMD Omega are bound to phospholipids—the same molecules that make up your cell membranes. This molecular compatibility may facilitate more efficient absorption and integration into cells compared to triglyceride-bound fish oil.
EPA & DHA for Complete Support
Get both essential omega-3 fatty acids. EPA supports cardiovascular health and healthy inflammatory response. DHA supports brain health, cognitive function, and retinal health. You need both for comprehensive omega-3 benefits.
Naturally Occurring Astaxanthin
Every serving includes 750mcg of astaxanthin, a powerful antioxidant that protects omega-3s from oxidation and provides additional cellular protection. Astaxanthin gives krill oil its natural reddish color.
NKO Krill Oil
We use Neptune Krill Oil (NKO), the original and most-studied krill oil brand. NKO is sourced from sustainable Antarctic krill fisheries with strict environmental standards and third-party certification.
40% Phospholipid Content
Not all krill oils are equal. Some contain as little as 20% phospholipids. SageMD Omega delivers 400mg phospholipids per serving (40% of total krill oil)—ensuring you get the bioavailability advantage krill oil offers.
No Fishy Aftertaste
Thanks to the phospholipid structure and astaxanthin content, krill oil is less prone to oxidation than fish oil. Most users report little to no fishy aftertaste or burps—a common complaint with traditional fish oil supplements.
Small, Easy-to-Swallow Softgels
Our softgels are smaller and easier to swallow than typical fish oil capsules. No more struggling with large, hard pills—just two small softgels with a meal.
Third-Party Tested
Every batch is tested by independent laboratories to verify omega-3 content, phospholipid levels, purity, and potency. You get exactly what the label promises, with no contaminants.
Made in USA
Manufactured in FDA-registered facilities following strict Good Manufacturing Practices (GMP).
SageMD Omega: Benefits That Build Over Time
Experience immediate cellular support and long-term omega-3 optimization with SageMD's phospholipid-bound krill oil.
Days 1-7
Absorption Begins
Within your first week, phospholipid-bound EPA and DHA begin integrating into your cell membranes. The phospholipid form may be absorbed more efficiently than triglyceride-bound fish oil, allowing faster incorporation into tissues.
Week 2
Cellular Integration Accelerates
By week two, omega-3 levels in your blood and tissues begin rising. The phospholipid structure facilitates integration into cell membranes throughout your body—in your heart, brain, joints, and blood vessels—where omega-3s provide their health benefits.
Week 3-4
Anti-Inflammatory Support Strengthens
As EPA accumulates in tissues, your body begins producing more specialized pro-resolving mediators (SPMs)—resolvins and protectins—that support healthy inflammatory response. Joint comfort may improve as your omega-6 to omega-3 ratio begins balancing.
Month 1-2
Omega-3 Index Improves
The omega-3 index—a measure of EPA and DHA in red blood cell membranes—begins rising. This marker is associated with cardiovascular health, and higher levels (above 8%) are linked to better heart health outcomes. Consistent supplementation is key to reaching optimal levels.
Month 2-3
Cardiovascular Benefits Strengthen
With sustained omega-3 intake, cardiovascular benefits become more pronounced. EPA and DHA support healthy endothelial function, help maintain normal triglyceride levels, and support healthy blood pressure already in normal range. Your heart cells benefit from improved membrane fluidity and function.
Month 3-6:
Brain and Cognitive Support Optimizes
DHA levels in brain tissue continue optimizing. Brain cell membrane fluidity improves, supporting neurotransmitter function, synaptic plasticity, and overall cognitive performance. Many people report improved mental clarity and focus with consistent omega-3 supplementation.
Month 6 & Beyond:
Long-Term Wellness Support
The benefits of consistent omega-3 supplementation continue accumulating over time. Maintaining optimal EPA and DHA levels supports cardiovascular health, brain function, joint comfort, and healthy aging. Think of omega-3s as a long-term investment in your cellular health.
SageMD Omega: Benefits That Build Over Time
Experience immediate cellular support and long-term omega-3 optimization with SageMD's phospholipid-bound krill oil.
Days 1-7
Absorption Begins
Within your first week, phospholipid-bound EPA and DHA begin integrating into your cell membranes. The phospholipid form may be absorbed more efficiently than triglyceride-bound fish oil, allowing faster incorporation into tissues.
Week 2
Cellular Integration Accelerates
By week two, omega-3 levels in your blood and tissues begin rising. The phospholipid structure facilitates integration into cell membranes throughout your body—in your heart, brain, joints, and blood vessels—where omega-3s provide their health benefits.
Week 3-4
Anti-Inflammatory Support Strengthens
As EPA accumulates in tissues, your body begins producing more specialized pro-resolving mediators (SPMs)—resolvins and protectins—that support healthy inflammatory response. Joint comfort may improve as your omega-6 to omega-3 ratio begins balancing.
Month 1-2
Omega-3 Index Improves
The omega-3 index—a measure of EPA and DHA in red blood cell membranes—begins rising. This marker is associated with cardiovascular health, and higher levels (above 8%) are linked to better heart health outcomes. Consistent supplementation is key to reaching optimal levels.
Month 2-3
Cardiovascular Benefits Strengthen
With sustained omega-3 intake, cardiovascular benefits become more pronounced. EPA and DHA support healthy endothelial function, help maintain normal triglyceride levels, and support healthy blood pressure already in normal range. Your heart cells benefit from improved membrane fluidity and function.
Month 3-6:
Brain and Cognitive Support Optimizes
DHA levels in brain tissue continue optimizing. Brain cell membrane fluidity improves, supporting neurotransmitter function, synaptic plasticity, and overall cognitive performance. Many people report improved mental clarity and focus with consistent omega-3 supplementation.
Month 6 & Beyond:
Long-Term Wellness Support
The benefits of consistent omega-3 supplementation continue accumulating over time. Maintaining optimal EPA and DHA levels supports cardiovascular health, brain function, joint comfort, and healthy aging. Think of omega-3s as a long-term investment in your cellular health.
60 DAY MONEY-BACK GUARANTEE
Your Heart, Brain, and Joints Will Thank You.
Try it risk-free! If you're not completely satisfied, simply return your order within 60 days for a full refund.
Discover the Benefits of SageMD Omega
Support your heart, brain, and joints with phospholipid-bound omega-3s from sustainable krill.
Support Cardiovascular Health
EPA and DHA help maintain healthy endothelial function, support normal cardiac rhythm, and help maintain healthy triglyceride levels already within normal range for comprehensive cardiovascular support.
Support Brain Health & Cognition
DHA is a major structural component of brain cell membranes. Phospholipid-bound DHA may cross the blood-brain barrier more efficiently, supporting memory, cognitive function, and brain health.
Support Joint Comfort & Flexibility
EPA supports healthy inflammatory response by serving as a precursor to resolvins and protectins—molecules your body makes to support natural inflammation resolution and joint comfort.
Enhanced Bioavailability
Phospholipid-bound omega-3s may be absorbed more efficiently than triglyceride forms because phospholipids match the molecular structure of your cell membranes, facilitating cellular integration.
Support Eye Health
DHA is the predominant omega-3 in retinal tissue. Adequate DHA status supports healthy retinal function, visual acuity, and long-term eye health as you age.
Antioxidant Protection
Astaxanthin protects omega-3s from oxidation and provides powerful antioxidant support throughout your body, concentrating in cell membranes to protect against oxidative damage.
Support Mood & Emotional Balance
Omega-3s, particularly EPA, play important roles in brain chemistry and neurotransmitter function. Adequate omega-3 status supports healthy mood and emotional well-being.
Sustainable & Pure
Sourced from Antarctic krill low on the food chain with minimal contaminant accumulation. Strictly regulated sustainable fishery with third-party certification for environmental responsibility.
SageMD Omega vs. Standard Fish Oil
See why phospholipid-bound omega-3s offer advantages over traditional triglyceride-based fish oil
Omega-3 form
Matches cell membrane structure
May enhance absorption efficiency
Contains astaxanthin antioxidant
40% phospholipid content
Sustainable Antarctic krill (NKO)
Low on food chain (fewer contaminants)
Minimal fishy aftertaste
Small, easy-to-swallow softgels
Third-party tested
SageMD Omega
Phospholipids
Fish Oil
Triglycerides
N/A
Varies
Varies
Varies
SageMD Omega vs. Standard Fish Oil
See why phospholipid-bound omega-3s offer advantages over traditional triglyceride-based fish oil
Omega-3 form
Matches cell membrane structure
May enhance absorption efficiency
Contains astaxanthin antioxidant
40% phospholipid content
Sustainable Antarctic krill (NKO)
Low on food chain (fewer contaminants)
Minimal fishy aftertaste
Small, easy-to-swallow softgels
Third-party tested
SageMD Omega
Phospholipids
Fish Oil
Triglycerides
N/A
Varies
Varies
Varies
Frequently Asked Questions
What's the difference between krill oil and fish oil?
The key difference is the molecular form of omega-3s. Fish oil contains EPA and DHA bound to triglycerides, while krill oil contains them bound to phospholipids. Phospholipids are the same type of molecules that make up your cell membranes, which may allow for more efficient absorption and integration into cells. Krill oil also naturally contains astaxanthin, a powerful antioxidant that protects the omega-3s and provides additional benefits. Additionally, krill are lower on the food chain than fish, so they accumulate fewer environmental contaminants.
How much EPA and DHA am I getting?
Each 2-softgel serving of SageMD Omega provides 135mg EPA and 60mg DHA, for a total of 195mg combined EPA+DHA. While this is less than some high-dose fish oil supplements, research suggests that phospholipid-bound omega-3s may be absorbed more efficiently than triglyceride forms, potentially allowing lower doses to achieve beneficial tissue levels.
Do I need more omega-3s than this provides?
It depends on your current diet and health goals. The American Heart Association recommends eating fatty fish twice per week, which provides roughly 500mg EPA+DHA daily. If you eat fish regularly, SageMD Omega provides additional support. If you rarely eat fish, you might consider taking 2-3 servings daily (4-6 softgels) to reach 400-600mg EPA+DHA, or alternating with fatty fish consumption. Consult your healthcare provider for personalized guidance.
What is phospholipid content and why does it matter?
Phospholipid content refers to the percentage of krill oil that consists of phospholipids (as opposed to triglycerides or free fatty acids). Higher phospholipid content means more omega-3s are bound to phospholipids rather than other forms. Research suggests that the bioavailability advantage of krill oil comes from its phospholipid content, so you want a krill oil with adequate phospholipid levels. SageMD Omega provides 40% phospholipid content (400mg per serving), which is significantly higher than many krill oils on the market that contain only 20-30%.
What is astaxanthin and what does it do?
Astaxanthin is a carotenoid antioxidant that gives krill (and salmon) their reddish-pink color. It's one of nature's most powerful antioxidants, with unique ability to span cell membranes and protect them from oxidative damage. In krill oil, astaxanthin serves dual purposes: it protects the omega-3s from oxidation (keeping them fresh and potent), and it provides additional antioxidant support to your cells. Astaxanthin has been studied for supporting eye health, skin health, exercise recovery, and cellular protection.
Is krill oil sustainable?
Yes, when sourced responsibly. SageMD Omega uses NKO (Neptune Krill Oil) from Antarctic krill fisheries that are strictly regulated for sustainability. The Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR) sets conservative catch limits that represent less than 1% of the estimated krill biomass. The fishery is certified by the Marine Stewardship Council (MSC) for sustainable practices. Antarctic krill is one of the most abundant species on Earth, and the fishery is carefully managed to protect the ecosystem.
Will I get fishy burps or aftertaste?
Most people taking krill oil report minimal to no fishy aftertaste or burps compared to fish oil. This is because the phospholipid structure and astaxanthin content make krill oil less prone to oxidation than fish oil. The fishy taste and burps from fish oil typically come from oxidation (rancidity). Always take SageMD Omega with food for best absorption and to minimize any potential aftertaste.
When should I take SageMD Omega?
Take 2 softgels daily with a meal that contains some fat. Omega-3s are fat-soluble, so they absorb better when taken with dietary fat. Many people take krill oil with breakfast or dinner. Consistency is more important than exact timing—just take it at the same time daily for best results.
Can I take this with other supplements?
Yes, krill oil can be taken alongside most other supplements. It pairs well with vitamin D (which is also fat-soluble and benefits from the dietary fat you consume with krill oil), multivitamins, and other omega-3 sources. If you're taking high-dose fish oil separately, check your total omega-3 intake to avoid excessive amounts. If you take blood thinners or antiplatelet medications, consult your healthcare provider before adding omega-3 supplements (see below).
Will this interact with blood thinners?
Omega-3 fatty acids can have mild antiplatelet effects (they reduce the tendency of blood to clot). If you take blood-thinning medications like warfarin (Coumadin), aspirin, clopidogrel (Plavix), or other anticoagulants/antiplatelets, consult your doctor before taking krill oil. Your doctor may need to monitor your bleeding time or adjust your medication dose. For most people at typical omega-3 doses, this interaction is mild, but it's important to check with your healthcare provider.
How long until I notice benefits?
Some benefits begin within days (absorption into cells), while others take weeks to months. Joint comfort improvements may be noticed within 2-4 weeks as EPA accumulates and supports healthy inflammatory response. Cardiovascular benefits develop over 1-3 months as omega-3 index improves. Brain health benefits are often subtle and develop over months of consistent supplementation. The key is consistency—omega-3 levels drop when you stop taking them, so ongoing supplementation provides ongoing benefits.
Can I take this if I'm allergic to shellfish?
Krill are crustaceans (like shrimp and lobster), so people with shellfish allergies should exercise caution. While krill oil is highly purified and contains minimal protein (the usual allergen in shellfish), allergic reactions are possible. If you have a shellfish allergy, do NOT take SageMD Omega without consulting your allergist or healthcare provider first. They may recommend allergy testing or suggest alternative omega-3 sources like algal oil.
Can I take this if I'm pregnant or breastfeeding?
Omega-3s, particularly DHA, are important during pregnancy and breastfeeding for fetal brain and eye development. However, you should consult your healthcare provider before starting any new supplement while pregnant or nursing. They can advise on appropriate omega-3 doses for your situation and may have specific recommendations about krill oil vs. fish oil vs. algal oil based on your individual needs.
Why are the softgels red?
The natural red-orange color comes from astaxanthin, the powerful antioxidant naturally present in krill. This is the same compound that gives salmon and shrimp their pink color. The red color is a good sign—it indicates the presence of this beneficial antioxidant. If krill oil softgels are completely clear or light yellow, they likely have lower astaxanthin content.
How should I store SageMD Omega?
Store in a cool, dry place away from direct sunlight and heat. Keep the bottle tightly closed. While not required, you can refrigerate krill oil if you prefer—the phospholipid structure remains stable at cold temperatures unlike some fish oils that can become cloudy. Keep out of reach of children.
What makes NKO krill oil special?
NKO (Neptune Krill Oil) is the original krill oil brand and the most-studied krill oil in clinical research. Many of the published studies on krill oil's benefits used NKO specifically. NKO has a proprietary extraction process that preserves the phospholipids and astaxanthin while ensuring purity. It's certified sustainable by the Marine Stewardship Council (MSC) and is manufactured to strict quality standards. When you see NKO on the label, you know you're getting the same krill oil used in published research.
Can children take SageMD Omega?
SageMD Omega is formulated for adults. Children have different omega-3 needs based on age, size, and developmental stage. Additionally, the softgels may be too large for young children. Consult your pediatrician for appropriate omega-3 supplements and dosing recommendations for children.
What if I miss a dose?
If you miss a dose, just take your regular dose the next day. Don't double up to make up for a missed dose. Omega-3 benefits come from consistent daily intake over time, so occasional missed doses won't significantly impact your results. The key is getting back to your regular routine.
Can I open the softgels?
While you can open softgels in theory, we don't recommend it. The softgel casing protects the krill oil from oxidation and makes it easier to swallow. Opening the softgels would expose the oil to air and give you the full taste of the oil (which most people prefer to avoid). If you have difficulty swallowing softgels, consider taking them with a larger sip of water or trying the "lean forward" technique where you lean forward while swallowing.
The Phospholipid Advantage: Why Molecular Form Matters
Most omega-3 supplements contain EPA and DHA bound to triglycerides because that's how they naturally occur in fish. But here's what most people don't know about how omega-3s work:
YOUR CELL MEMBRANES ARE MADE OF PHOSPHOLIPIDS:
Every cell in your body is surrounded by a membrane made primarily of phospholipids. When omega-3s integrate into these membranes, they support membrane fluidity, cell signaling, and numerous cellular functions that protect your health.
THE TRIGLYCERIDE PROBLEM:
When you take fish oil (triglyceride-bound omega-3s), your body must:
Break down the triglycerides to release EPA and DHA
Absorb the free fatty acids
Rebuild them into phospholipids
Finally incorporate them into cell membranes
This multi-step process requires metabolic energy and enzymes—and not everyone does this efficiently.
THE PHOSPHOLIPID SOLUTION:
Krill oil contains omega-3s already bound to phospholipids—the same molecules that make up your cell membranes. Research suggests this molecular compatibility may allow:
More efficient absorption in the digestive tract
Faster incorporation into cell membranes
Better omega-3 utilization at lower doses
RESEARCH FINDINGS:
A 2011 study by Schuchardt et al. compared identical doses of EPA+DHA from fish oil (triglyceride form) vs. krill oil (phospholipid form) and found a trend toward higher incorporation into plasma phospholipids with krill oil. While differences didn't reach statistical significance in this small study, the trend suggests phospholipid-bound omega-3s may be absorbed more efficiently.
More recent network meta-analyses examining multiple studies have found that krill oil formulations with higher phospholipid content show superior bioavailability compared to fish oil, particularly at lower doses (under 2000mg daily).
THE TAKEAWAY:
The molecular form of omega-3s matters. Phospholipid-bound omega-3s from krill may offer bioavailability advantages over triglyceride-bound fish oil, potentially allowing your body to achieve optimal omega-3 status more efficiently.